Buy Augmentin online
Augmentin is indicated to treat bacterial infections of lower respiratory tract, otitis media, sinusitis skin infections and urinary tract infections.
Augmentin general information
Augmentin is a combined broad-spectrum antibiotic used to treat bacterial infections of the respiratory tract (bronchitis, pneumonia, bronchopneumonia), ENT organs (otitis, sinusitis, tonsillitis, pharyngitis), skin and subcutaneous tissue (abscess, phlegmon, cellulitis, wound ), urinogenital system (cystitis, urethritis, pyelonephritis, salpingitis, vaginitis, gonorrhea, endometritis), as well as osteomyelitis, sepsis and peritonitis. In addition, Augmentin is used for the prevention and treatment of infections after surgery.
The composition of all varieties and dosage forms Augmentina as active ingredients include the following two substances:
- Clavulanic acid.
Amoxicillin and clavulanic acid in various forms of Augmentin are contained in different dosages and ratios of each other, which allows you to choose the optimal amount of active substances for each case and age of a person.
Amoxicillin is an antibiotic belonging to the penicillins group, which has a wide spectrum of action and has a destructive effect on a large number of pathogenic bacteria that cause infectious diseases of various organs and systems. In addition, amoxicillin is well tolerated and rarely causes side effects, which makes this antibiotic safe, effective and approved for use even in pregnant women and infants.
However, it has one drawback — resistance to amoxicillin in many bacteria after several days of use forms resistance, since microbes begin to produce special substances — lactamase, which destroy the antibiotic. This disadvantage limits the use of amoxicillin in the treatment of bacterial infections.
However, the lack of amoxicillin is eliminated with clavulanic acid, which is Augmentin’s second component. Clavulanic acid is a substance that inactivates lactamase produced by bacteria and, accordingly, makes amoxicillin effective even against microbes that were previously insensitive to its action. That is, clavulanic acid makes amoxicillin effective against bacteria that were resistant to its action, which significantly expands the range of application of the combined drug Augmentin.
Thus, the combination of amoxicillin + clavulanic acid makes the antibiotic more effective, expands its spectrum of action and prevents the development of resistance on the part of bacteria.
Augmentin Dosage (for adults and children)
Each Augmentin dosage form contains two active ingredients — amoxicillin and clavulanic acid, therefore the dosage of the drug is indicated not by one number, but by two, for example, 400 mg + 57 mg, etc. Moreover, the first digit always indicates the amount of amoxicillin, and the second — clavulanic acid.
Thus, Augmentin in the form of a powder for preparing a solution for injection is available in dosages of 500 mg + 100 mg and 1000 mg + 200 mg. This means that after dilution of the powder with water, a solution is obtained which contains 500 mg or 1000 mg of amoxicillin and, respectively, 100 mg and 200 mg of clavulanic acid. In everyday life, these dosage forms usually denote simply «Augmentin 500» and «Augmentin 1000», using a number that reflects amoxicillin content and omits the amount of clavulanic acid.
Augmentin in powder form for oral suspension is available in three dosages: 125 mg + 31.25 mg per 5 ml; 200 mg + 28.5 mg per 5 ml and 400 mg + 57 mg per 5 ml. In everyday life, the designation of the amount of clavulanic acid is usually omitted, and only the content of amoxicillin is indicated, since the dosage is calculated precisely by antibiotic. Due to this, short designations of suspensions of various dosages look like this: «Augmentin 125», «Augmentin 200» and «Augmentin 400».
The dosage of Augmentin suspensions is per 5 ml: that is, 125 mg per 5 ml, 200 mg per 5 ml and 400 mg per 5 ml. The content of the active substance in terms of 5 ml means that after preparing the suspension from powder, it is 5 ml (and not 1 ml) of the prepared solution that will contain 125 mg, 200 mg or 400 mg of amoxicillin.
Since Augmentin suspension is used in children under 12 years of age, it is often referred to as «child Augmentin.» Accordingly, the dosage of the suspension is also called children’s. In fact, the dosage of the suspension is standard and may well be used in adults with low body mass, but because of the predominant use of this form of the drug for children, they are called children’s.
Augmentin tablets are available in three dosages: 250 mg + 125 mg; 500 mg + 125 mg and 875 mg + 125 mg, differing only in the content of amoxicillin. Therefore, in everyday life, tablets are usually designated shortened, indicating only the dosages of amoxicillin: Augmentin 250, Augmentin 500 and Augmentin 875. The indicated amount of amoxicillin is contained in one Augmentin tablet.
Augmentin EC is available in powder form for the preparation of suspensions in a single dosage — 600 mg + 42.9 mg per 5 ml. This means that in 5 ml of the finished suspension contains 600 mg of amoxicillin and 42.9 mg of clavulanic acid.
Augmentin SR is produced in the form of tablets with a single dosage of active substances — 1000 mg + 62.5 mg. This means that one tablet contains 1000 mg of amoxicillin and 62.5 mg of clavulanic acid.
Augmentin has one therapeutic effect — antibacterial, since it has a detrimental effect on a wide range of different pathogenic microbes that cause infectious and inflammatory diseases of the urinary and respiratory tract, skin and subcutaneous tissue, as well as osteomyelitis, sepsis and peritonitis. That is, Augmentin destroys the bacteria that provoke infections of these organs and, accordingly, cures infectious and inflammatory diseases.
The presence of clavulanic acid in Augmentin makes the drug highly effective, because it allows you to expand the spectrum of action of amoxicillin and make it effective against bacteria, which, when used in isolation, can be resistant to this antibiotic.
Indications for use
Indications for use of suspensions, tablets and injections Augmentin
All Augmentin dosage forms are indicated for the treatment of various infections caused by microorganisms sensitive to it. So, suspension, tablets and injections have the same indications for use:
- Infections of the upper respiratory tract and upper respiratory tract (otitis, sinusitis, tonsillitis), including recurrent (except tablets 250 mg + 125 mg);
- Lower respiratory tract infections (bronchitis, bronchopneumonia, lobar pneumonia, empyema, lung abscess), including exacerbation of chronic processes;
- Infections of the genitourinary system in men and women (cystitis, urethritis, pyelonephritis, endometritis, vaginitis, adnexitis, salpingitis, salpingo-oophoritis, tubular abscess, pelviperitonitis, chancroid, gonorrhea);
- Infections of the skin and soft tissues (cellulitis, abscess, phlegmon, boils, panniculitis, infected wounds);
- Infections of bones and joints (osteomyelitis);
- Odontogenic infections (periodontitis, maxillary sinusitis, dental and maxillary abscesses with cellulitis) — only tablets 500 mg + 125 mg and 875 mg + 125 mg;
- Mixed infections of various organs (septic abortion, postpartum sepsis, intra-abdominal sepsis, septicemia, peritonitis, cholangitis, cholecystitis, postoperative infections) — only for tablets of all dosages.
Augmentin’s injections are also indicated for the prevention and treatment of infections that can develop after major surgeries on the organs of the digestive tract, pelvis, head, neck, kidneys, cardiovascular surgery, and after implantation of prostheses in organs.
Indications for use Augmentin suspension
Indications for use Augmentin suspension is a short-term treatment of the following infections caused by microbes that are sensitive to the antibiotic:
- Recurrent or acute otitis media;
- Lobar pneumonia and bronchopneumonia;
- Infections of the skin and soft tissues (cellulitis, abscess, phlegmon, boils, panniculitis, infected wounds).
Indications for use of Augmentin tablets
The indications for the use of Augmentation tablets are a short-term treatment of the following infections, triggered by bacteria sensitive to the antibiotic:
- Pneumonia is not a hospital;
- Exacerbation of chronic bronchitis;
- Acute bacterial sinusitis;
- Prevention of infectious complications after dental operations.
Augmentin — instructions for use
Tablets should be swallowed whole, without chewing, without breaking through and crushing in any other way, but with a small amount of water (half a glass).
Before taking the suspension, measure the required amount using a special measuring cap or syringe with graduations. Suspension is taken orally by swallowing the measured required amount directly from the measuring cap. For children who for some reason cannot drink a clean suspension, it is recommended to dilute it with water in a 1: 1 ratio, after having poured the necessary amount from the measuring cap into a glass or other container. After use, the measuring cap or syringe should be rinsed with clean water.
In order to reduce discomfort and side effects from the gastrointestinal tract, it is recommended to take tablets and suspension at the beginning of a meal. However, if this is not possible for any reason, then the tablets can be taken at any time regarding food, since the food does not have a significant effect on the effects of the drug.
Augmentin injections produce only intravenously. You can enter the solution of streamer (from a syringe) or infusion («dropper»). Intramuscular administration of the drug is not allowed! The solution for injection is prepared from the powder immediately before administration and is not stored even in the refrigerator.
Taking tablets and suspensions, as well as intravenous administration of Augmentin solution should be made at regular intervals. For example, if you need to take the drug twice a day, you should maintain the same 12-hour interval between doses. If it is necessary to take Augmentin 3 times a day, then it should be done every 8 hours, trying to strictly observe this interval, etc.
The minimum allowable course of application of any form and variety of Augmentin is 5 days. This means that you can not take the drug for less than 5 days. The maximum allowable duration of application of any form and variety of Augmentin without repeated examinations is 2 weeks. That is, after the diagnosis, without re-examination, you can take the drug for no longer than 2 weeks. If, during the course of therapy, a re-examination was performed, which revealed a positive, but slow cure rate, on the basis of these results, the duration of Augmentin’s treatment may be increased to 3 or even 4 weeks.
If necessary, a step therapy can be performed, consisting in the sequential application of injections and tablets or suspensions inside. At the same time, at first, in order to obtain the maximum effect, Augmentin injections are made, and then they switch to taking pills or suspension.
You should not replace the various forms and dosages of Augmentin on each other, for example, instead of one tablet 500 mg + 125 mg take 2 tablets 250 mg + 125 mg, etc. Such replacements cannot be made, since different dosages of even the same form of the drug are not equivalent. Since there is a wide choice of Augmentin dosages, you should always choose the right one, rather than use the existing one, trying to replace it with the necessary one.